文章基本信息

标题：Patterns of organization of actin and myosin in normal and transformed cultured cells
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作者：R Pollack ; M Osborn ; K Weber 等
期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：1975
卷号：72
期号：3
页码：994-998
DOI：10.1073/pnas.72.3.994
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：The patterns of distribution of intracellular actin and myosin were examined by specific immunofluorescence in a series of normal, simian-virus-40-transformed, and revertant cell lines of rat and mouse origin. A consistent correlation was found between sensitivity to anchorage-dependent growth control and the presence of large, thick sheaths of actin-containing material. The presence of these sheaths was temperature-dependent in a rat line transformed by a temperature-sensitive mutant in the complementation group A of the oncogenic virus simian virus 40.