文章基本信息

标题：The Presence of I-Region-Associated Antigens on B Cells in Molecules Distinct from Immunoglobulin and H-2K and H-2D
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作者：Emil R. Unanue ; Martin E. Dorf ; Chella S. David 等
期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：1974
卷号：71
期号：12
页码：5014-5016
DOI：10.1073/pnas.71.12.5014
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：The distribution of I-region-associated antigenic specificities in murine lymphoid cells was studied by immunofluorescence. The antigens were mostly represented in B cells and in macrophages. The complexes of I-anti-I-region-associated antigens were found to be distributed throughout the lymphocyte surface both at 4{degrees} and 37{degrees}. In about two-thirds of the lymphocytes the complexes redistributed into caps after incubation with a second ligand (an anti-mouse immunoglobulin). The I-region specificities were in molecules distinct from immunoglobulin or from the molecules coded by the H-2K and H-2D regions.
关键词：lymphocytes ; histocompatibility antigens ; surface molecules ; immunogenetics