文章基本信息

标题：Developmentally Regulated, Carbohydrate-Binding Protein in Dictyostelium discoideum
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作者：Steven D. Rosen ; John A. Kafka ; David L. Simpson 等
期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：1973
卷号：70
期号：9
页码：2554-2557
DOI：10.1073/pnas.70.9.2554
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：A carbohydrate-binding protein assayed by its ability to agglutinate formalinized sheep erythrocytes is synthesized between 3 and 9 hr after Dictyostelium discoideum cells are deprived of food, as the cells become cohesive. Agglutination of erythrocytes by this protein was inhibited by N-acetyl-D-galactosamine, D-galactose, and L-fucose, but other monosaccharides had little or no effect. The protein bound completely to Sepharose 4B, and was isolated in highly purified form by elution with D-galactose. It appears to be present on the surface of cohesive but not vegetative slime-mold cells. The possibility that this protein may mediate intercellular adhesion in Dictyostelium is considered.
关键词：cellular slime mold ; morphogenesis ; intercellular recognition ; lectin