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  • 标题:Nucleotide Sequence of HS-β Satellite DNA from Kangaroo Rat Dipodomys ordii
  • 本地全文:下载
  • 作者:K. Fry ; R. Poon ; P. Whitcome
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1973
  • 卷号:70
  • 期号:9
  • 页码:2642-2646
  • DOI:10.1073/pnas.70.9.2642
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:The sequence of the highly repetitive satellite HS-{beta} DNA fraction from kangaroo rat Dipodomys ordii was determined independently by RNA and DNA sequencing techniques. A basic iterated sequence of 10 nucleotides with several mutational variations was found. Base-composition data are consistent with the proposed sequence and revealed a high content of 5-methylcytosine. DNA and RNA sequencing techniques used gave identical results, showing that the fidelity of synthesis of riboguanidine-substituted DNA under our conditions is adequate for nucleotide sequence studies.
  • 关键词:ribosubstitution ; DNA sequence analysis ; RNA sequence analysis ; RNA polymerase ; Cot
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