文章基本信息

标题：Discrimination between Messenger Ribonucleic Acids by a Mammalian Translation Initiation Factor
本地全文：下载
作者：U. Nudel ; B. Lebleu ; M. Revel 等
期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：1973
卷号：70
期号：7
页码：2139-2144
DOI：10.1073/pnas.70.7.2139
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：A factor from rabbit-reticulocyte ribosome, which stimulates by 5-fold initiation of hemoglobin mRNA translation in Krebs ascites cell extracts, was purified to homogeneity. The factor, a protein of about 65,000 molecular weight in sodium dodecyl sulfate, discriminates between various mRNAs: it stimulates translation of [α] globin mRNA and of tobacco mosaic virus RNA, but has only a small effect on {beta} globin mRNA and no effect at all on Mengo virus RNA translation.
关键词：reticulocyte initiation factors ; hemoglobin synthesis ; Krebs ascites extracts