文章基本信息

标题：Biosynthesis of Reticulocyte Membrane Proteins by Membrane-Free Polyribosomes
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作者：Harvey F. Lodish
期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：1973
卷号：70
期号：5
页码：1526-1530
DOI：10.1073/pnas.70.5.1526
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：Intact rabbit reticulocyte cells synthesize two predominant species of membrane polypeptides; at least 10 reticulocyte membrane polypeptide species are not produced by the cells. Cell-free extracts of reticulocytes, free of any membranes or membrane-bound polyribosomes, synthesize large amounts of these two membrane polypeptides; one of these polypeptides appears to be modified, probably by loss of 20-40 amino acids, after it is incorporated into the membrane. Deprivation of hemin results in inhibition of synthesis by lysates of membrane proteins, globin, and all other cytoplasmic proteins.
关键词：rabbit ; hemin ; globin ; gel electrophoresis