文章基本信息

标题：A Crystalline Fragment of the Double Helix: The Structure of the Dinucleoside Phosphate Guanylyl-3′,5′-Cytidine
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作者：Roberta Ogilvie Day ; Nadrian C. Seeman ; John M. Rosenberg 等
期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：1973
卷号：70
期号：3
页码：849-853
DOI：10.1073/pnas.70.3.849
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：The sodium salt of guanylyl-3'-5'-cytidine crystallizes in a monoclinic unit cell with one molecule in the asymmetric unit. Each molecule is related to another molecule by a 2-fold rotation axis which results in the formation of an antiparallel, right-handed double helix with complementary hydrogen bonding between the guanine and cytosine residues. The crystal is heavily hydrated with 36 water molecules in the unit cell. The geometry of this crystalline double helix is very similar to those which have been derived from studies of fiber x-ray diffraction patterns of double-stranded RNA, even though the latter do not yield data at atomic resolution.
关键词：x-ray diffraction ; complementary hydrogen bonding ; dinucleoside phosphate ; right-handed helix