文章基本信息

标题：Demonstration of a Cell-Surface Antigen Associated with Murine Sarcoma Virus by Immunoelectron Microscopy
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作者：T. Aoki ; J. R. Stephenson ; S. A. Aaronson 等
期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：1973
卷号：70
期号：3
页码：742-746
DOI：10.1073/pnas.70.3.742
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：Cells transformed by murine sarcoma virus have been examined for the presence of a new virus-associated cell-surface antigen by immunoelectron microscopy. A common antigen has been detected on the surface of nonproductively transformed cells that were induced by two different strains of murine sarcoma virus, Kirsten and Moloney. This antigen shows crossreaction with cell lines transformed by murine sarcoma virus that were produced in two different mammalian species, rats and mice. Further, this antigen is distinct from previously described antigens on the surfaces of cells infected by murine leukemia virus, on the viral envelope, and on the surfaces of spontaneously transformed cell lines or cell lines transformed by x-irradiation.
关键词：Kirsten and Maloney strains ; MuLV ; viral envelope antigens