文章基本信息

标题：In Vivo Production of an RNA-DNA Copolymer after Infection of Escherichia coli by Bacteriophage T4
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作者：Patrick J. Buckley ; Linda D. Kosturko ; Andrzej W. Kozinski 等
期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：1972
卷号：69
期号：11
页码：3165-3169
DOI：10.1073/pnas.69.11.3165
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：An RNA-DNA copolymer was isolated from Escherichia coli infected with bacteriophage T4. The RNA and DNA are covalently linked, and in the same polynucleotide strand. The DNA of the copolymer hybridizes specifically to the left strand of phage T4 DNA. The copolymer is produced in cells infected with amber mutants of phage T4 deficient in DNA replication and is not inhibited by the addition of chloramphenicol.
关键词：initiation ; hybridization ; DNA replication ; chloramphenicol ; density gradient