文章基本信息

标题：Microelectrophoretic Application of Cholinergic Compounds, Protein Oxidizing Agents, and Mercurials to the Chemically Excitable Membrane of the Electroplax
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作者：J. Del Castillo ; E. Bartels ; J. A. Sobrino 等
期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：1972
卷号：69
期号：8
页码：2081-2085
DOI：10.1073/pnas.69.8.2081
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：Cholinergic compounds, protein oxidizing agents, heavy metal ions, and organic mercurials were microelectrophoretically (or electro-osmotically) applied to the innervated surface of the isolated electroplax of Electrophorus electricus. Phasic potential changes, resembling those observed under similar conditions in frog muscle, followed not only pulses of the common cholinergic drugs, but were also elicited by o-iodosobenzoate, p-chloromercuribenzoate, and Hg++ ions. These results suggest that cholinergic receptors of both the electroplax and amphibian endplates behave in essentially the same manner. The discrepancies previously observed can be attributed mainly to the different techniques of drug application.
关键词：acetylcholine ; o -iodosobenzoate ; p -chloromercuribenzoate ; Mg⁺⁺ ; electro-osmotic technique