文章基本信息

标题：A Transition to a Compact Form of DNA in Polymer Solutions
本地全文：下载
作者：L. S. Lerman
期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：1971
卷号：68
期号：8
页码：1886-1890
DOI：10.1073/pnas.68.8.1886
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：In the presence of over-threshold concentrations of simple neutral polymers and salts, DNA undergoes a cooperative change in its solution structure. Sedimentation studies at low DNA concentrations show that phage DNA molecules collapse into particles approaching the compactness of the contents of phage heads. The interaction between DNA and polymers is thought to be nonspecifically replusive.
关键词：poly(vinyl pyrrolidinone) ; poly(ethylene oxide) ; T4 phage ; centrifugation