首页    期刊浏览 2025年01月10日 星期五
登录注册

文章基本信息

  • 标题:Crystallization of a common cold virus, human rhinovirus 14: “Isomorphism” with poliovirus crystals
  • 本地全文:下载
  • 作者:John W. Erickson ; Elizabeth A. Frankenberger ; Michael G. Rossmann
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1983
  • 卷号:80
  • 期号:4
  • 页码:931-934
  • DOI:10.1073/pnas.80.4.931
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:Crystals of rhinovirus 14 have been grown reproducibly. They diffract x-rays to a resolution of at least 3.5 A. The orthorhombic crystal unit cell contains two virions, each situated on a crystallographic twofold axis. At less than 30-A resolution, the space group approximates to 1222 with the particles possessing 222 pseudo crystallographic symmetry. The crystals are "isomorphous" with type I polio crystals [Finch, J. T. & Klug, A. (1959) Nature (London) 183, 1709-1714; Hogle, J. M. (1982) J. Mol. Biol. 160, 663-668], suggesting some similarities of structure between enteroviruses and rhinoviruses.
  • 关键词:picornavirus structure ; x-ray diffraction ; reproducibly grown crystals ; high-resolution data
国家哲学社会科学文献中心版权所有