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  • 标题:Stereospecific chemoattraction of lymphoblastic cells by gradients of lysophosphatidylcholine
  • 本地全文:下载
  • 作者:R D Hoffman ; M Kligerman ; T M Sundt
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1982
  • 卷号:79
  • 期号:10
  • 页码:3285-3289
  • DOI:10.1073/pnas.79.10.3285
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:Human plasma contains chemoattractant activity for cultured cells from the mouse thymic lymphoma 6C3HED and also for lymphoblasts from concanavalin A-stimulated mouse spleen cells. A major portion of the attractant activity for both cell types could be attributed to plasma lysophosphatidylcholine. Studies on synthetic lysophosphatides showed that polar head group structure, acyl chain length, and stereochemical configuration are important determinants for attractant activity.
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