文章基本信息

标题：Single-molecule measurements of importin α/cargo complex dissociation at the nuclear pore
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作者：Changxia Sun ; Weidong Yang ; Li-Chun Tu 等
期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：2008
卷号：105
期号：25
页码：8613-8618
DOI：10.1073/pnas.0710867105
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：Macromolecules are transported between the cytoplasm and the nucleoplasm of eukaryotic cells through nuclear pore complexes (NPCs). Large (more than {approx}40 kDa) transport cargoes imported into the nucleus typically form a complex with at least one soluble transport cofactor of the importin (Imp) {beta} superfamily. Many cargoes require an accessory cofactor, Imp {alpha
关键词：FRET ; nuclear transport ; single-molecule fluorescence