文章基本信息

标题：Evolution and development of facial bone morphology in threespine sticklebacks
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作者：Charles B. Kimmel ; Bonnie Ullmann ; Charline Walker 等
期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：2005
卷号：102
期号：16
页码：5791-5796
DOI：10.1073/pnas.0408533102
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：How do developmental mechanisms evolve to control changing skeletal morphology, the shapes and sizes of individual bones? We address this question with studies of the opercle (OP), a large facial bone that has undergone marked morphological evolution in the ray-finned fish. Attributes for developmental analysis motivated us to examine how OP shape and size evolve and develop in threespine sticklebacks, a model system for understanding vertebrate evolution. We find that when Alaskan anadromous fish take up permanent residence in lakes, they evolve smaller and reshaped OPs. The change is a reduction in the amount of bone laid down along one body axis, and it arises at or shortly after the onset of OP development. A quantitative trait locus is present on linkage group 19 that contributes in a major way to this phenotype.
关键词：quantitative trait locus ; major effect locus ; opercle craniofacial patterning ; hyoid arch