文章基本信息

标题：β-Arrestin inhibits NF-κB activity by means of its interaction with the NF-κB inhibitor IκBα
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作者：D. Scott Witherow ; Tiffany Runyan Garrison ; William E. Miller 等
期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：2004
卷号：101
期号：23
页码：8603-8607
DOI：10.1073/pnas.0402851101
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：In addition to their roles in desensitization and signaling of seven-membrane-spanning receptors, {beta}-arrestins have been more recently implicated in regulating non-seven-membrane-spanning receptor pathways. By using a yeast two-hybrid screen, we identified the inhibitor of NF-{kappa}B, I{kappa}B{alpha