文章基本信息

标题：Attitudes toward medication and the clinical variables in schizophrenia: Structural equation models
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作者：Alessandro Rossi ; Roberta Pacifico ; Paolo Stratta 等
期刊名称：Patient Preference and Adherence
印刷版ISSN：1177-889X
电子版ISSN：1177-889X
出版年度：2009
卷号：3
页码：305-309
DOI：10.2147/PPA.S5590
出版社：Dove Medical Press Ltd
摘要：Objective: Our study uses data from a large clinical trial to further dissect the contributors attitude toward antipsychotic medication measured with the Drug Attitude Inventory (DAI) in schizophrenia. Method: A total of 227 consecutive outpatients (140 males, 87 females) with schizophrenia or schizoaffective disorder according to DSM-IV criteria were evaluated. Structural equation models (SEM) were used to examine the relationship between attitudes toward medication as measured with the DAI and clinical variables assessed by Positive and Negative Syndrome Scale (PANSS) and Global Assessment of Functioning (GAF). Results: Among four models, the data better fit a model in which attitudes toward medication (DAI-30) was predicted by PANSS Positive and Insight measures, and GAF (goodnessof-fit = 0.99). Conclusion: The data best fit a model where the most complex interaction of insight measures and positive symptoms does predict attitudes toward medication.
关键词：attitude toward medication; drug attitude inventory; structural equation models