文章基本信息

标题：It's not what you say but the way that you say it: an fMRI study of differential lexical and non-lexical prosodic pitch processing
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作者：Derek K Tracy ; David K Ho ; Owen O'Daly 等
期刊名称：BMC Neuroscience
印刷版ISSN：1471-2202
电子版ISSN：1471-2202
出版年度：2011
卷号：12
期号：1
页码：128
DOI：10.1186/1471-2202-12-128
语种：English
出版社：BioMed Central
摘要：This study aims to identify the neural substrate involved in prosodic pitch processing. Functional magnetic resonance imaging was used to test the premise that prosody pitch processing is primarily subserved by the right cortical hemisphere. Two experimental paradigms were used, firstly pairs of spoken sentences, where the only variation was a single internal phrase pitch change, and secondly, a matched condition utilizing pitch changes within analogous tone-sequence phrases. This removed the potential confounder of lexical evaluation. fMRI images were obtained using these paradigms. Activation was significantly greater within the right frontal and temporal cortices during the tone-sequence stimuli relative to the sentence stimuli. This study showed that pitch changes, stripped of lexical information, are mainly processed by the right cerebral hemisphere, whilst the processing of analogous, matched, lexical pitch change is preferentially left sided. These findings, showing hemispherical differentiation of processing based on stimulus complexity, are in accord with a 'task dependent' hypothesis of pitch processing.
关键词：Temporal Cortex ; Inferior Frontal Gyrus ; Superior Temporal Gyrus ; Inferior Parietal Lobule ; Middle Frontal Gyrus