The end of the Cold War era coincided with the beginning of a shift Iran’s foreign policy from the ideological to the pragmatic. The collapse of the Soviet Union created an important geopolitical region in the north of Iran. The dialogue doors were opened by Khatami’s “dialogue among civilizations” in contrast to the “clash of civilizations”. With the election of Bush and especially after the September 11th attacks, the US code was changed from globalist to regionalist. In this period Iran, was named as one of three countries in the “Axis of Evil”. After 2005, the Iranian policy towards the US changed fundamentally so that Israel and the US were seen as the main enemies of Iran. Also, Iran’s nuclear issue aggravated the hostility and it was used by the US to maximize its hegemony. In this context, the US efforts to impose its geopolitical codes on other countries to be involved in conducting its policies against Iran could be justified. It was also regarded as a geopolitical imperative, Today, the US has to curb Iran’s ideological-political activities and if both Iran and the United States do not scale down their demands, military confrontation could be predictable.