文章基本信息

标题：A neurophysiological approach to effects induced by accelerated particles on the central nervous system in mice
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作者：Stefano LOIZZO ; Luisa LOPEZ ; Giovanni PEDRAZZO 等
期刊名称：Annali dell'Istituto Superiore di Sanita
印刷版ISSN：0021-2571
出版年度：2002
卷号：38
期号：04
出版社：Editrice Kurtis Srl
摘要：Summary. - This experiment was designed to study mechanisms of "phosphene vision”. A beam of accelerated carbon particles (energy 100 and 300 MeV/n) was delivered into retina and sensorimotor cortex of anaesthetised mice bearing chronic electrodes. Cycles of light flashes were also administered. Following accelerated particles stimulation cycles to the retina, 500 to 5000 per stimulus, 30 stimuli per cycle, stimulus time-related brain waveforms in mice cortex were recorded. Their amplitude and latency appeared to be related to the energy delivered. The short waveforms latency (~30 ms), and the lack of retinic potentials and oscillatory potentials following particles stimuli suggest that the impact of accelerated particles does not produce activation of retinic chemical structures.
关键词：Key words: accelerated particles, phosphenes, evoked responses, f-VEP (flash-visual evoked potential), ERG (electroretinogram), visual system, cortex, flash.