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标题：Study of the effects of electroacupuncture in a rodent model of cerebral ischaemia
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作者：Maria Rosaria DOMENICI (a) ; Luo Mingfu (b) ; Maria Teresa TEBANO (a) 等
期刊名称：Annali dell'Istituto Superiore di Sanita
印刷版ISSN：0021-2571
出版年度：2003
卷号：39
期号：03
出版社：Editrice Kurtis Srl
摘要：Summary. - The effects of electroacupuncture (EA) has been studied in a model of global cerebral ischaemia performed in gerbils through the bilateral carotid artery occlusion (BCAO). Animals, under isofluorane anaesthesia, underwent 5 min of BCAO and were killed after 7 days. The effects of EA were evaluated both on functional (with electrophysiological recordings of synaptic potentials in hippocampal slices) and morphological parameters (by counting the number of survived neurons in CA1 area of the hippocampus). The results demonstrated that the treatment of animals with EA (5 min before, during and 20 min after BCAO and 30 min per day in the following 5 days) did not modify either the ischaemia-induced reduction of synaptic potentials amplitude, either ischaemia-induced neuronal loss in the hippocampus. We conclude that, at least in this animal model of cerebral ischaemia, EA does not exert a neuroprotective effect.
关键词：Key words: electroacupuncture, cerebral ischaemia, hippocampus, gerbils