This paper examines institutional practice regarding integration of mobile technologies into electronic teaching that has previously depended on computers alone. More specifically, this study explores challenges, opportunities and constraints reflected in efforts to transition from reliance on formal learning management systems for course development and delivery toward the infusion of media targeted to students' mobile devices. Based on three e-course case histories, this paper illustrates how the participants’ university is addressing the transformational challenges found in the study and examines instructor perceptions about University support. The researchers conducted two in-depth semi-structured interviews which took place at different times to reflect the longitudinal experiences of the three participants over time. Main findings of the research suggest that institutional faculty need technical support, training and professional development to understand not only how to work with mobile devices but also the means to achieve clear instructional purposes with them