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  • 标题:Vitamin D, Sunlight Exposure, and Bone Density in Elderly African American Females of Low Socioeconomic Status
  • 本地全文:下载
  • 作者:Sally P. Weaver ; Cindy Passmore ; Ben Collins
  • 期刊名称:Family Medicine
  • 印刷版ISSN:0742-3225
  • 电子版ISSN:1938-3800
  • 出版年度:2010
  • 卷号:42
  • 期号:01
  • 出版社:Society of Teachers of Family Medicine
  • 摘要:

    BACKGROUND AND OBJECTIVES: Darker skin pigmentation and aging are known factors influencing the body's ability to synthesize adequate amounts of vitamin D (25OHD). The objective of this study is to determine the 25OHD insufficiency in elderly African American females of low socioeconomic status (SES) in a southern latitude during springtime sun exposure. METHODS: Patients > 70 years old who did not have disorders that might affect vitamin D and calcium absorption/metabolism were enrolled at a community health center. Serum calcium, 25OHD, and intact parathyroid hormone were measured and repeated 6--8 weeks later. Bone mineral density (BMD) scan results were obtained from clinic records. RESULTS: Most subjects (86.4%) had inadequate 25OHD levels < 32ng/mL, and no clinically significant rise in levels was seen after 6--8 weeks of sun exposure. A quarter of subjects had truly deficient 25OHD levels < 15ng/mL. 25OHD levels were positively correlated with BMD only at the lumbar spine. Fifty-two percent of subjects were osteopenic, and 9% were osteoporotic. CONCLUSIONS: 25OHD insufficiency is common among low SES elderly African American women, and springtime sunlight exposure does not cause significant increases in 25OHD. Additionally, this population has low calcium and vitamin D intake from diet, and more women than expected had reduced BMD

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