文章基本信息

标题：SNP'ing for Longevity
本地全文：下载
作者：Jan Vijg
期刊名称：Aging
出版年度：2009
卷号：01
期号：05
出版社：U.S.Department of Health & Human Service
摘要：Medieval alchemists, craving the boon of youth and desiring renewed health and strength, were kept busy searching for the mythical elixir of life, a universal medicine supposedly containing a recipe for rejuvenescence. Now, in the 21st century, their modern successors use the fruits of the genomics revolution to discover genetic factors that ward off aging and aging-related diseases. In this issue of Aging, Gravina et al. [1] present evidence that the long life span of the more fortunate among us could be related to variants of the p21 cell cycle inhibitor.
关键词：Single nucleotide polymorphism; centenarians; aging; p21; genome instability