Gastrointestinal tract is commonly affected by tuberculosis; however isolated tuberculous
involvement of the rectum is rare. We report a relatively uncommon case of isolated rectal
tuberculosis in a 31 year old female, who presented with rectal bleeding and painful defaecation.
It clinically and radiologically mimicked malignancy but biopsy showed tuberculosis. Patient
was started on AntiKoch’s treatment (AKT) and patient responded well. A brief discussion of
the case and review of literature is presented.