文章基本信息

标题：Infectious etiology in atherosclerosis – from hypothesis to certainty?
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作者：Doina Azoicăi ; Luminiţa Smaranda Iancu
期刊名称：Journal of Preventive Medicine
印刷版ISSN：1582-5388
出版年度：2001
卷号：9
期号：1
出版社：Institute of Public Health, Iasi
摘要：Experimental pathological studies and clinical surveys made in order to estimate the atherogenic role of some pathogens underlined the intervention of Cytomegalovirus (1978), Chlamydia pneumoniae (1988) and Helicobacter pylori (1994) in the generation and evolution of the specific vascular injuries. A causal relationship between these microorganisms and atherosclerosis though supported by clinical evidence is limited by the encountered difficulties both in the evaluation of infectious case history and microbiological diagnosis as well as the unknown prevalence of antibodies owner in general population. In Romania , few prevalence serological screenings for C. pneumoniae , Cytomegalovirus and H. pylori have been made due to the high costs and difficult methodologies. The validation of this causality-related hypothesis would allow the orientation of the cardiovascular diseases prevention programmes towards the avoidance or neutralization of the influence both the non-infectious and microbial factors.
关键词：atherosclerosis, risk factor, infection, seroprevalence