摘要:The transfusion transmitted infections are potentially dangerous
complications of transfusion therapy in immunocompromised patients. The aim of
this study was to determine the prevalence of transmissible infections in blood
donor population in Kashan, Iran. A total of 600 consecutive sera were tested
for CMV-IgM antibody, HBsAg, hepatitis B core (HBc) antibody, hepatitis C (HCV)
antibody, and HIV antibody with standard methods. Of the sera tested, 14
specimens (2.3%) were CMV-IgM positive. The frequency of seropositive revealed
no significant differences between male and female donors. The frequency rates
of CMV-IgM seropositive tests tend to decline with increasing the age. There was
no relation between the frequency rates of CMV-IgM seropositive with the
educational level, socioeconomic status, marital status, urban dweller and rural
resident patients. The prevalence of HBV, HCV, and HIV antibody was 0.5%, 0.5%,
and 0%, respectively. These findings implied important clinical applications
because detection of CMV positive sera may reduce the risk for transmission of
CMV in blood transfusion and thereby decrease the risk on CMV-induced
complications.
关键词:Hepatitis C ، HIV ، CMV ، Seroprevalence ، Blood donors