As the National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP), Centers for Disease Control and Prevention (CDC), celebrates its 20th anniversary, we highlight the critical intersection of maternal and child health and chronic disease prevention. Twenty years ago, as luck — or prescient leadership — would have it, the Division of Reproductive Health (DRH) became part of the newly formed chronic disease center. Leaders inside and outside CDC have occasionally puzzled over why reproductive health work was co-located with topics such as tobacco control, diabetes, cancer, and nutrition.