文章基本信息

标题：Pushing it back. Dating the CCR5–32 bp deletion to the Mesolithic in Sweden and its implications for the Meso\Neo transition
本地全文：下载
作者：Kerstin Lidén ; Anna Linderholm ; Anders Götherström 等
期刊名称：Documenta Praehistorica
印刷版ISSN：1408-967X
电子版ISSN：1854-2492
出版年度：2006
卷号：13
出版社：Department of Archaeology, Faculty of Arts, University of Ljubljana
摘要：Genetic variation in the chemokine receptor gene CCR5 has received considerable scientific interest during the last few years. Protection against HIV-infection and AIDS, together with specific geographic distribution are the major reasons for the great interest in CCR5 32bp deletion. The event for the occurrence of this mutation has been postulated by coalescence dating to the 14th century, or 5000 BP. In our prehistoric Swedish samples we show that the frequency of 32pb deletion in CCR5 in the Neolithic population does not deviate from the frequency in a modern Swedish population, and that the deletion existed in Sweden already during the Mesolithic period.