文章基本信息

标题：Increasing Spectrum in Antimicrobial Resistance of Shigella Isolates in Bangladesh: Resistance to Azithromycin and Ceftriaxone and Decreased Susceptibility to Ciprofloxacin
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作者：Rahman, Mahbubur ; Shoma, Shereen ; Rashid, Harunur 等
期刊名称：Journal of Health, Population and Nutrition
出版年度：2007
卷号：25
期号：2
页码：158-167
出版社：ICDDR,B: Centre for Health and Population Research
摘要：Antimicrobial resistance of Shigella isolates in Bangladesh, during 2001-2002, was studied and compared with that of 1991-1992 to identify the changes in resistance patterns and trends. A significant increase in resistance to trimethoprim-sulphamethoxazole (from 52% to 72%, p<0.01) and nalidixic acid (from 19% to 51%, p<0.01) was detected. High, but unchanged, resistance to tetracycline, ampicillin, and chloramphenicol, low resistance to mecillinam (resistance 3%, intermediate 3%), and to emergence of resistance to azithromycin (resistance 16%, intermediate 62%) and ceftriaxone/cefixime (2%) were detected in 2001-2002. Of 266 recent isolates, 63% were resistant to ≥3 anti-Shigella drugs (multidrug-resistant [MDR
关键词：Azithromycin; Ciprofloxacin; Drug resistance, Microbial; E-test; Microbial sensitivity tests; Nalidixic acid; R-plasmid; Shigella; Bangladesh