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标题：Iodresorption bei antiseptischer Anwendung von Iodophoren und Schlussfolgerungen zur Risikobewertung
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作者：Below H, Brauer VFH, Kramer A
期刊名称：GMS Krankenhaushygiene Interdisziplinär
印刷版ISSN：1863-5245
出版年度：2007
卷号：02
期号：02
出版社：German Medical Science GMS Publishing House, Düsseldorf
摘要：Iodophore are the most commonly used antiseptics and scrubbing agents and were of important support to implement the renaissance of antisepsis. In the beginning of the 1980s there were no alternative antiseptic agents in place. However, at that time experts already requested a risk-benefit analysis of PVP-iodine due to possible harmful side effects. In these days there are other antiseptics established demonstrating a better therapeutic index due to a favourable balance between microbicidal efficacy and side effects. Moreover, these antiseptics (i.e. octenidine and polihexanide) will not be absorbed unlike iodophores. Iodophores are able to induce thyroid disorders since there is a considerable ability to absorb iodine through skin, mucous membranes and wounds. This article summarizes the current knowledge of indications and contraindications as well as provides a risk-benefit analysis of using iodophores as antiseptics.
关键词：PVP iodine, absorption, skin, mucous membranes, wounds, thyroid dysorders, indications, side effects, use restrictions, contraindications