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标题：Mikrobiozide Wirksamkeit von Polihexanid
本地全文：下载
作者：Koburger T ; Müller G ; Eisenbeiß W 等
期刊名称：GMS Krankenhaushygiene Interdisziplinär
印刷版ISSN：1863-5245
出版年度：2007
卷号：02
期号：02
出版社：German Medical Science GMS Publishing House, Düsseldorf
摘要：When tested in the quantitative suspension test according to the prEN 12054, polihexanide meets the requirements defined by this standard for an antiseptic. At a product concentration of 0.02%, the test organisms are reduced by ≥5 lg, or ≥3 lg under dirty conditions, respectively, within a contact time of 5 min. This agrees well with the accepted recommendation of 0.02% polihexanide for the application on chronic wounds. In the presence of sesamoid bone/cartilage a polihexanide concentration of 0.005% is sufficient effective. As this concentration does not appear to have any adverse effects it might be promising to analyze its suitability for the antiseptic irrigation of joints in the animal model. The combination of 0.1% polihexanide with undecylenamidopropyl betaine (Prontosan®) possesses the antiseptic properties specified above, too. However, with regard to the higher concentration of polihexanide, at least a repeated application of this formulation cannot be recommended for cleansing and irrigating wounds or burns.