文章基本信息

标题：Indikationen und Wirkstoffauswahl zur antiseptischen Therapie sekundär heilender Wunden
本地全文：下载
作者：Kramer A ; Müller G ; Assadian O 等
期刊名称：GMS Krankenhaushygiene Interdisziplinär
印刷版ISSN：1863-5245
出版年度：2006
卷号：01
期号：01
出版社：German Medical Science GMS Publishing House, Düsseldorf
摘要：For chronic wounds to become primarily healing wounds, not only the appropriate surgical procedure - especially wound debridement - but also the treatment of the causative basic disease must be taken into consideration. In both the prophylaxis of wound infections and the treatment of existing wound infections, wound antiseptics play a crucial role. As long as a clinically manifest infection is confined to the wound and has not spread hematogenically, the indication for application of wound antiseptics is given. Should systemic involvement exist, antimicrobial chemotherapy is additionally required. Antiseptics must only be used following careful determination of indication. Impaired wound healing can otherwise result. For chronically poorly healing wounds and burns, polihexanide is the agent of first choice. However, based on new in-vitro findings, octenidine dihydrochloride is superior to polihexanide in terms of therapeutic spectrum. These findings enable a broader application of octenidine dihydrochloride to include use on chronic wounds at lower concentrations than usual. The following agents must be viewed critically in terms of their use as wound antiseptics: chlorhexidine, 8-chinolinol, nitrofural, phenol derivates, quats, silver nitrate, silver sulphadiazine, tosylchloramide sodium, triclosan, and hydrogen peroxide. As wound antiseptics, dyes and organic mercury compounds are obsolete.