标题：Effect of Differne Inspired Oxygen Concentrations During Casarean Section Under Spinal Anaesthesia on maternal and Foetal Oxygenation and Lipid Perozidation
摘要：This study was planned to evaluate the effects of different inspired oxygen concentrations in 60 non-labouring patients scheduled for elective caesarean section divided in 3 groups (21% i.e. atmospheric air for group I, 35% for group II and 60% for group III) on blood gas analysis and lipid peroxidation markers before and at the time of delivery for mothers and in umbilical vein and artery for foetuses. It was found that the increase in inhaled oxygen concentration is associated with an increase in maternal and foetal PO2, plasma malondialdehyde and 8-isoprostane (p < 0.01). In foetuses, significant rise in malondialdehyde and uric acid levels was seen with 60% of inhaled oxygen concentration only. Thus breathing high inspired oxygen concentration by the mother increases maternal and foetal oxygenation but also causes concomitant increase in oxygen free radical activity in both mother and foetus which may have consequences in their later life.
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