文章基本信息

标题：Development of the ATAQ-IPF: a tool to assess quality of life in IPF
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作者：Jeffrey J Swigris ; Sandra R Wilson ; Kathy E Green 等
期刊名称：Health and Quality of Life Outcomes
印刷版ISSN：1477-7525
电子版ISSN：1477-7525
出版年度：2010
卷号：8
期号：1
页码：77
DOI：10.1186/1477-7525-8-77
语种：English
出版社：BioMed Central
摘要：There is no disease-specific instrument to assess health-related quality of life (HRQL) in patients with idiopathic pulmonary fibrosis (IPF). Patients' perspectives were collected to develop domains and items for an IPF-specific HRQL instrument. We used item variance and Rasch analysis to construct the ATAQ-IPF (A Tool to Assess Quality of life in IPF). The ATAQ-IPF version 1 is composed of 74 items comprising 13 domains. All items fit the Rasch model. Domains and the total instrument possess acceptable psychometric characteristics for a multidimensional questionnaire. The pattern of correlations between ATAQ-IPF scores and physiologic variables known to be important in IPF, along with significant differences in ATAQ-IPF scores between subjects using versus those not using supplemental oxygen, support its validity. Patient-centered and careful statistical methodologies were used to construct the ATAQ-IPF version 1, an IPF-specific HRQL instrument. Simple summation scoring is used to derive individual domain scores as well as a total score. Results support the validity of the ATAQ-IPF, and future studies will build on that validity.
关键词：Idiopathic Pulmonary Fibrosis ; Interstitial Lung Disease ; Domain Score ; Supplemental Oxygen ; Idiopathic Pulmonary Fibrosis Patient