文章基本信息

标题：Evaluation of health outcomes in osteoarthritis patients after total knee replacement: a two-year follow-up
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作者：Feng Xie ; Ngai-Nung Lo ; Eleanor M Pullenayegum 等
期刊名称：Health and Quality of Life Outcomes
印刷版ISSN：1477-7525
电子版ISSN：1477-7525
出版年度：2010
卷号：8
期号：1
页码：87
DOI：10.1186/1477-7525-8-87
语种：English
出版社：BioMed Central
摘要：To quantify the improvement in health outcomes in patients after total knee replacement (TKR). This was a two-year non-randomized prospective observational study in knee osteoarthritis (OA) patients undergone TKR. Patients were interviewed one week before, six months after, and two years after surgery using a standardized questionnaire including the SF-36, the Oxford Knee Score (OKS), and the Knee Society Clinical Rating Scale (KSS). A generalized estimating equation (GEE) model was used to estimate the magnitudes of the changes with and without the adjustment of age, ethnicity, BMI, and years with OA. A total of 298 (at baseline), 176 (at six-months), and 111 (at two-years) eligible patients were included in the analyses. All the scores changed significantly over time, with the exception of SF-36 social functioning, vitality, and mental health. With the adjustment of covariates, the magnitude of changes in these scores was similar to those without the adjustment. Both general and knee-specific physical functioning had been significantly improved after TKR, while other health domains have not been substantially improved after the surgery.
关键词：Physical Functioning ; Total Knee Replacement ; Generalize Estimate Equation ; Oxford Knee Score ; Physical Functioning Score