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标题：Health related quality of life six months following surgical treatment for secondary peritonitis – using the EQ-5D questionnaire
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作者：Kimberly R Boer ; Oddeke van Ruler ; Johannes B Reitsma 等
期刊名称：Health and Quality of Life Outcomes
印刷版ISSN：1477-7525
电子版ISSN：1477-7525
出版年度：2007
卷号：5
期号：1
页码：35
DOI：10.1186/1477-7525-5-35
语种：English
出版社：BioMed Central
摘要：To compare health related quality of life (HR-QoL) in patients surgically treated for secondary peritonitis to that of a healthy population. And to prospectively identify factors associated with poorer (lower) HR-QoL. A prospective cohort of secondary peritonitis patients was mailed the EQ-5D and EQ-VAS 6-months following initial laparotomy. Multicenter study in two academic and seven regional teaching hospitals. 130 of the 155 eligible patients (84%) responded to the HR-QoL questionnaires. HR-QoL was significantly worse on all dimensions in peritonitis patients than in a healthy reference population. Peritonitis characteristics at initial presentation were not associated with HR-QoL at six months. A more complicated course of the disease leading to longer hospitalization times and patients with an enterostomy had a negative impact on the mobility (p = 0.02), self-care (p < 0.001) and daily activities: (p = 0.01). In a multivariate analysis for the EQ-VAS every doubling of hospital stay decreases the EQ-VAS by 3.8 points (p = 0.015). Morbidity during the six-month follow-up was not found to be predictive for the EQ-5D or EQ-VAS. Six months following initial surgery, patients with secondary peritonitis report more problems in HR-QoL than a healthy reference population. Unfavorable disease characteristics at initial presentation were not predictive for poorer HR-QoL, but a more complicated course of the disease was most predictive of HR-QoL at 6 months.
关键词：Peritonitis ; Intensive Care Unit Stay ; Secondary Peritonitis ; Mannheim Peritonitis Index ; Longe Intensive Care Unit Stay