文章基本信息

标题：Are mean platelet volume and splenomegaly subclinical inflammatory marker in children with familial mediterranean fever?
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作者：Ismail Dursun ; Faysal Gok ; Oguzhan Babacan 等
期刊名称：Health
印刷版ISSN：1949-4998
电子版ISSN：1949-5005
出版年度：2010
卷号：2
期号：7
页码：692-695
DOI：10.4236/health.2010.27105
出版社：Scientific Research Publishing
摘要：The present study aimed to investigate the correlation of MPV and splenomegaly as inflammation activity of FMF patients at the attacks free period. We retrospectively reviewed the medical records of 43 patients with FMF. This study was performed at the attack free period as clinical and laboratory. For this study, patients were divided into two groups. Patients with splenomegaly is called group 1 (n = 12) and patients with no splenomegaly is called group 2 (n = 31). Groups were compared respect to age, gender, platelet counts, acute phase reactants and MPV. The mean MPV (fl) were significantly higher in group 1 (8.9 ± 0.8) than in group 2 (8.4 ± 0.5, p < 0.05). This study suggested that increased MPV and splenomegaly without amyloidosis could be a sign of chronic inflammation in children with FMF even in attack free period.
关键词：Familial Mediterranean Fever; Mean Platelet Volume; Subclinical Inflammation