文章基本信息

标题：Postnatal Weight Gain and Onset of Puberty in Rats Exposed to Aqueous Extract of Hibiscus sabdariffa in Utero
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作者：Eghosa ; E. Iyare ; Olufeyi A. Adegoke 等
期刊名称：Pakistan Journal of Nutrition
印刷版ISSN：1680-5194
电子版ISSN：1994-7984
出版年度：2008
卷号：7
期号：1
页码：98-101
DOI：10.3923/pjn.2008.98.101
出版社：Asian Network for Scientific Information
摘要：The present study was designed to investigate whether or not maternal consumption of aqueous extract of Hibiscus sabdariffa (HS) during pregnancy has any effect on the growth and onset of puberty in the female offspring. Eighteen in-bred virgin female Sprague-Dawley rats aged between 10-12 weeks and weighing 125Â±5.5g (meanÂ±SEM) with two consecutive regular 4-day estrus cycle were randomly assigned to one of three groups of 6 rats/group. One group had tap water (control); another had 1.5g-extract/kg while the third group had 3.0g-extract/kg in their drinking water throughout pregnancy. Results showed that HS consumption during pregnancy significantly decreased maternal fluid and food intake , increased postnatal weight gain and delays the onset of puberty in the female offspring.