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标题：Some Biochemical, Haematological and Histological Responses to a Long Term Consumption of Telfairia occidentalis- Supplemented Diet in Rats
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作者：Emeka ; E.J. Iweala ; Onyechi Obidoa 等
期刊名称：Pakistan Journal of Nutrition
印刷版ISSN：1680-5194
电子版ISSN：1994-7984
出版年度：2009
卷号：8
期号：8
页码：1199-1203
DOI：10.3923/pjn.2009.1199.1203
出版社：Asian Network for Scientific Information
摘要：Some biochemical, haematological and histological responses were studied in rats undergoing a long term feeding with a Telfairia occidentalis- supplemented diet. Biochemical and hematological parameters investigated included serum protein, total cholesterol, lipid peroxidation , haemoglobin, white blood cells, Aspartate aminotransferase, Alanine aminotransferase, Alkaline phosphatase, Glutathione-s-transferase and Superoxide dismutase. Histological changes associated with Telfairia occidentalis- supplemented diet on the liver, intestine and testes were also examined. Results showed that Telfairia occidentalis- supplemented diet caused a significant increase (p<0.05) in weight and haemoglobin. Cholesterol and lipid peroxidation were significantly reduced (p<0.05). There were however no significant changes in the enzymes including Aspartate aminotransferase, Alanine aminotransferase, Alkaline phosphatase, Glutathione-s-transferase and Superoxide dismutase. Only Alkaline phosphatase was significantly reduced (p<0.05). Histological changes showed hypertrophy of the intestinal propia and reduced globlet cells while the testes exhibited thick basement membrane and large spermatogonia.