摘要:Introduction. Today, there is a negative tendency of increasing the number of preschool children with disharmonious psychophysical development in Ukraine (55.9% in 1998, 59.4% in 2005). At the same time, society offers actual solutions of this problem. Under certain conditions, the development of preschool children of this category can improve or approach to healthy peers’ development level, and within existing educational systems, this process can be managed. Therefore, it is important to study the indicators of physical condition children with special needs in order to substantiate preventive and health measures, determine the content of physical exercises for correction of their psychophysical development. Methods: analysis, generalization of literary sources data; pedagogical ascertainment experiment; medical and biological methods; methods of mathematical statistics. Purpose. To determine physical condition indicators of preschool children with disabilities in psychophysical development. Result and discussion. The value of morbidity children with disabilities of both genders, regardless of the defect, indicate unsatisfactory level. At the surveyed children was noted deterioration of the cardiovascular system functional conditions, that characterized by a slight increase in resting heart rate. Most of the surveyed children reported unsatisfactory quality of cardiovascular system regulation (92.0% girls, 75.8% boys). The values of endurance coefficients of the surveyed children with special needs, regardless of the defect, indicate a weakening of the cardiovascular system. External respiratory indicators of children with speech disorders, mental retardation, Down syndrome and autism spectrum disorders correspond to a level below average. Only peers with musculoskeletal disorders have an average level. Conclusions. The biological age of the surveyed contingent corresponds to the passport. It has been confirmed that the development of children with psychophysical disabilities is conditioned by the lag of the normative in most indicators. This leads to functional impairment of some physiological systems. It is was found marked decreasing in cardiovascular and respiratory system activity children with autism spectrum disorders, Down syndrome and with mental retardation.