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标题：Short-term Changes in Ocular Surface pH after 23-gauge Microincision Vitrectomy Surgery
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作者：Jun Ho Oh ; Su Jin Park ; Dong Jin Kang 等
期刊名称：Journal of the Korean Ophthalmological Society
印刷版ISSN：0378-6471
出版年度：2021
卷号：62
期号：2
页码：216-221
DOI：10.3341/jkos.2021.62.2.216
出版社：The Korean Ophthalmological Society
摘要：Purpose This study aimed to investigate changes in ocular surface pH after 23-gauge microincision vitrectomy surgery. Methods This retrospective study included 42 patients who underwent 23-gauge microincision vitrectomy. Best-corrected visual acuity and intraocular pressure were measured. Fundus examination, color fundus photography, and spectral-domain optical coherence tomography were performed. Chemosis was evaluated once a day after surgery, and the ocular surface pH was measured using a microelectrode on the day before surgery and every day up to day 5 after surgery. Results A total of 42 eyes in 42 patients were examined. The average age was 63.7 years. The indications for surgery included epiretinal membrane in 14 eyes (33.3%), vitreous hemorrhage in 11 eyes (26.2%), macular hole in 11 eyes (26.2%), and rhegmatogenous retinal detachment in six eyes (14.3%). Although the mean ocular surface pH increased from 7.12 ± 0.04 to 7.55 ± 0.04 on the first day after surgery ( p < 0.001), it gradually decreased to 7.41 ± 0.03 from the second day postoperatively ( p < 0.001). It was subsequently measured as 7.33 ± 0.04 on the third day ( p < 0.001) and 7.23 ± 0.03 on the fourth day ( p < 0.001) postoperatively. On the fifth postoperative day, the ocular surface pH further decreased to 7.15 ± 0.03 ( p = 0.152) and recovered to the preoperative state. A statistically significant correlation was found between the change in ocular surface pH and the chemosis grade ( p = 0.001). Conclusions After 23-gauge microincision vitrectomy surgery, the ocular surface pH shifted temporarily in the alkaline direction within a physiological range correlated with chemosis and intravitreal tamponade usage.
其他关键词：23-gauge microincision vitrectomy surgery, Chemosis, Ocular surface pH, Tamponade