文章基本信息

标题：The Characteristics of Women with Subsequent Distal Radius Fracture after Initial Distal Radius Fracture
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作者：Jongjin Lee ; Jae Kwang Kim ; Minyoung Oh 等
期刊名称：Journal of Bone Metabolism
印刷版ISSN：2287-6375
出版年度：2021
卷号：28
期号：2
页码：123-129
DOI：10.11005/jbm.2021.28.2.123
出版社：The Korean Society for Bone and Mineral Research
摘要：BACKGROUND :The purpose of this study was to investigate the characteristics of women with subsequent distal radius fracture (DRF) and to compare bone fragility variables in women with initial and subsequent DRF. METHODS :We enrolled 227 women who experienced DRF (203 women with initial DRF and 24 women with subsequent DRF) between September 2016 and April 2019. We compared demographic characteristics and bone fragility variables, including bone mineral density, trabecular bone score, hip geometry, bicortical thickness of the distal radius, and fracture risk assessment tool (FRAX) scores between the 2 groups. To reduce bias, patients with subsequent DRF were propensity score-matched in a 1:2 manner with patients affected by initial DRF, and additional comparisons were performed. RESULTS :Patients in the subsequent DRF group were older than those in the initial DRF group, but this difference was not significant (P=0.091). The proportion of patients receiving treatment with osteoporosis medication was significantly higher in the subsequent DRF group (41.7% vs. 19.2%, P=0.011). Bone fragility variables did not differ significantly between the 2 groups. However, the ten-year probability of major osteoporotic fractures based on FRAX scores was significantly higher in patients with subsequent DRF (7.5% vs. 10.8%, P<0.001). Similar results were observed when comparing the propensity score-matched initial and subsequent DRF groups. CONCLUSIONS :These findings suggest that the occurrence of subsequent DRF after initial DRF can be attributed to multiple factors rather than bone fragility alone. Systematic and multidisciplinary management would be helpful in preventing the occurrence of subsequent DRF after the initial DRF.
关键词：Bone density;Hip geometry;Osteoporosis;Radius fractures;Trabecular bone score