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标题：Evaluation of anti-tyrosinase activity of Allium ursinum extracts and their metal complexes [pdf]
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作者：Mohammad Nikkhahi ; Effat Souri ; Parisa Sarkhail 等
期刊名称：Acta Scientarum Polonorum - Technologia Alimentaria
印刷版ISSN：1644-0730
电子版ISSN：1898-9594
出版年度：2018
卷号：17
期号：3
页码：219-226
DOI：10.17306/J.AFS.2018.0585
出版社：Agricultural University of Poznan Press
摘要：Background. A. ursinum is found to contain high levels of some beneficial phenolic and poly phenolic compounds were found to be effective in scavenging DPPH radicals and tyroinase inhibition. The aim of this study was to evaluate the anti-tyrosinase and antioxidant activity of three different extracts from the ultrasound-assisted method and their metal complexes from A. ursinum to discover new candidates for food additives, cosmetic and pharmaceutical products. Material and methods. Water, 70% ethanol and absolute ethanol extract of Allium ursinum and their manganese and zinc-complexes were characterized by FT-IR and UV-Vis spectra and their antioxidant and antityrosinase activity determined using DPPH radical scavenging and mushroom tyrosinase assay. Results. The antioxidant activity of the water extract was superior to other samples, while the 70% ethanol extract exhibited the highest anti-tyrosinase activity. Metal complex formation of the extracts led to a significantly lower antioxidant effect. The tyrosinase inhibition strongly related to the metal ion and extraction solvent. All the zinc complexes had lower anti-tyrosinase activity than their extracts, while the manganese complex of the water and absolute ethanol extracts exhibited higher anti-tyrosinase activity than related extracts. Conclusion. This study shows that Mn complex of A. ursinum extracts, based on the solvent extraction, could increase tyrosinase inhibition activity and could be a good candidate for intended cosmetic applications and food additives.
其他关键词：Allium ursinum, antioxidant, anti-tyrosinase, metal complex, phenolic compounds