文章基本信息

标题：Metallic ion release from biocompatible cobalt-based alloy
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作者：Ivana Dimic ; Ivana Cvijovic-Alagic ; Ivana Kostic 等
期刊名称：Chemical Industry and Chemical Engineering Quarterly
印刷版ISSN：1451-9372
出版年度：2014
卷号：20
期号：4
页码：571-577
DOI：10.2298/CICEQ130813039D
出版社：Association of the Chemical Engineers
摘要：Metallic biomaterials, which are mainly used for the damaged hard tissue replacements, are materials with high strength, excellent toughness and good wear resistance. The disadvantages of metals as implant materials are their susceptibility to corrosion, the elastic modulus mismatch between metals and human hard tissues, relatively high density and metallic ion release which can cause serious health problems. The aim of this study was to examine metallic ion release from Co-Cr-Mo alloy in artificial saliva. In that purpose, alloy samples were immersed into artificial saliva with different pH values (4.0, 5.5 and 7.5). After a certain immersion period (1, 3 and 6 weeks) the concentrations of released ions were determined using Inductively Coupled Plasma - Mass Spectrophotometer (ICP-MS). The research findings were used in order to define the dependence between the concentration of released metallic ions, artificial saliva pH values and immersion time. The determined released metallic ions concentrations were compared with literature data in order to describe and better understand the phenomenon of metallic ion release from the biocompatible cobalt-based alloy.
关键词：metallic biomaterials; cobalt-based alloy; ion release; artificial saliva; pH value