文章基本信息

标题：Biosensors Coupled with Signal Amplification Technology for the Detection of Pathogenic Bacteria: A Review
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作者：Fengchun Huang ; Yingchao Zhang ; Jianhan Lin 等
期刊名称：Biosensors
电子版ISSN：2079-6374
出版年度：2021
卷号：11
期号：6
页码：190
DOI：10.3390/bios11060190
出版社：MDPI Publishing
摘要：Foodborne disease caused by foodborne pathogens is a very important issue in food safety. Therefore, the rapid screening and sensitive detection of foodborne pathogens is of great significance for ensuring food safety. At present, many research works have reported the application of biosensors and signal amplification technologies to achieve the rapid and sensitive detection of pathogenic bacteria. Thus, this review summarized the use of biosensors coupled with signal amplification technology for the detection of pathogenic bacteria, including (1) the development, concept, and principle of biosensors; (2) types of biosensors, such as electrochemical biosensors, optical biosensors, microfluidic biosensors, and so on; and (3) different kinds of signal amplification technologies applied in biosensors, such as enzyme catalysis, nucleic acid chain reaction, biotin-streptavidin, click chemistry, cascade reaction, nanomaterials, and so on. In addition, the challenges and future trends for pathogenic bacteria based on biosensor and signal amplification technology were also discussed and summarized.
关键词：foodborne pathogens; biosensor; signal amplification; food safety foodborne pathogens ; biosensor ; signal amplification ; food safety