首页    期刊浏览 2024年12月05日 星期四
登录注册

文章基本信息

  • 标题:Acute Bronchiolitis Treatment: A Comparison of Montelukast, Aminophylline and Ventolin in Pediatric Patients: A Clinical Trial Study
  • 本地全文:下载
  • 作者:Gholamreza Soleimani ; Elham Shafighi Shahri ; seyed hosein soleimanzadeh mousavi
  • 期刊名称:International Journal of Pediatrics
  • 印刷版ISSN:2345-5047
  • 电子版ISSN:2345-5055
  • 出版年度:2021
  • 卷号:9
  • 期号:6
  • 页码:13683-13690
  • DOI:10.22038/ijp.2020.51086.4055
  • 出版社:Mashhad University of Medical Sciences
  • 摘要:Background: The effects of various drugs on reducing the severity of bronchiolitis symptoms in children have been identified. We sought to make a comparison of Montelukast, Aminophylline and Ventolin (Intravenous Salbutamol) in the treatment of acute bronchiolitis in patients ranged between 1 and 24 months old. Materials and Methods: This study used a randomized clinical trial method. Statistical population of the study included all patients younger than 2 years and older than one month who were admitted to Ali-Ibn-Abitaleb Hospital in Zahedan-Iran. Two hundred patients were divided into four groups using a random number table method. The first group received supplemental monotherapy with Montelukast 4 mg/kg daily for 7 days. The second group received 1 mg/kg Aminophylline injection every 12 hours. The third group or the control group received supportive measures. The fourth group received 0.15 mg/kg Ventolin Nebules with dose of 2.5 mg. Symptoms were measured on days 2, 5 and 7, and the number of hospital admissions days was also assessed in four groups and compared. Results: The results showed that the consumption of Montelukast and Ventolin Nebules had no significant effect on bronchiolitis treatment in comparison with the control group (P>0.05). Using Aminophylline did not reduce the symptoms of bronchiolitis in comparison with the control group (p <0.05). The results also showed that using aminophylline in group B did not produce better results in decreasing the severity of the symptoms of bronchiolitis in comparison with Montelukast group and Ventolin group (p <0.05). Conclusion The results showed that consumption of Aminophylline, Montelukast and Ventolin had no significant effect on bronchiolitis in comparison with the control group.
  • 关键词:Aminophylline ; Bronchiolitis ; Montelukast ; Pediatric ; Ventolin
国家哲学社会科学文献中心版权所有