文章基本信息

标题：N-Acyltriazinedione; a Novel Acylating Reagent Synthesized from a Triazinone-Type Condensing Reagent
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作者：Kohei Yamada ; Jeongsu Lee ; Mika Kota 等
期刊名称：Chemical and Pharmaceutical Bulletin
印刷版ISSN：0009-2363
电子版ISSN：1347-5223
出版年度：2021
卷号：69
期号：5
页码：498-502
DOI：10.1248/cpb.c20-00952
出版社：The Pharmaceutical Society of Japan
摘要：In this paper, we report the synthesis of N -acyltriazinedione via the unexpected O – N acyl rearrangement of acyloxytriazinone and its utility as an acylating reagent. N -Acyltriazinedione can be isolated by silica gel column chromatography and reacts with amines in the absence of any base to give the corresponding amides in good yields.
关键词：acylating reagent;triazinedione;O–N acyl rearrangement