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标题：Data on the Quantification of Aspartate, GABA and Glutamine Levels in the Spinal Cord of Larval Sea Lampreys after a Complete Spinal Cord Injury
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作者：Blanca Fernández-López ; Natividad Pereiro ; Anunciación Lafuente 等
期刊名称：Data
印刷版ISSN：2306-5729
出版年度：2021
卷号：6
期号：6
页码：54-58
DOI：10.3390/data6060054
出版社：MDPI Publishing
摘要：We used high-performance liquid chromatography (HPLC) methods to quantify aspartate, GABA, and glutamine levels in the spinal cord of larval sea lampreys following a complete spinal cord injury. Mature larval sea lampreys recover spontaneously from a complete spinal cord transection and the changes in neurotransmitter systems after spinal cord injury might be related to their amazing regenerative capabilities. The data presented here show the concentration of the aminoacidergic neurotransmitters GABA (and its precursor glutamine) and aspartate in the spinal cord of control (non-injured) and 2-, 4-, and 10-week post-lesion animals. Statistical analyses showed that GABA and aspartate levels significantly increase in the spinal cord four weeks after a complete spinal cord injury and that glutamine levels decrease 10 weeks after injury as compared to controls. These data might be of interest to those studying the role of neurotransmitters and neuromodulators in recovery from spinal cord injury in vertebrates.
关键词：aspartate; GABA; glutamine; HPLC; spinal cord injury; lampreys aspartate ; GABA ; glutamine ; HPLC ; spinal cord injury ; lampreys