文章基本信息

标题：Efectos de la suplementación con vitamina D sobre el control glucémico en pacientes prediabéticos: una revisión sistemática
其他标题：Effects of vitamin D supplementation on the glycemic control of pre-diabetic individuals: a systematic review
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作者：Lima, Carlos Henrique Ribeiro ; Lavôr, Layanne Cristina de Carvalho ; Nogueira, Nadir do Nascimento 等
期刊名称：Nutrición Hospitalaria
印刷版ISSN：0212-1611
出版年度：2021
卷号：38
期号：1
页码：186-193
DOI：10.20960/nh.03309
出版社：Aula Médica Ediciones
摘要：Introduction: research shows the potential effect of vitamin D supplementation with an improvement in the glycemic profile of pre-diabetic patients. Objective: this study evaluates the effects of vitamin D supplementation on glycemic control markers in pre-diabetic individuals. Methods: we analyzed studies published over the last ten years, and indexed in the Science Direct, PubMed, and LILACS databases. We searched studies using health descriptors related to vitamin D, pre-diabetes, and glycemic control markers. We considered randomized controlled trials eligible for inclusion. All phases of selection, data extraction, and risk of bias assessment were carried out by two independent evaluators. Results: we identified 309 articles, of which 4 met the inclusion criteria. Of these, 3 studies have shown that vitamin D supplementation does not alter glycemic control markers in pre-diabetic individuals. Only one study showed a positive effect after supplementation with 60,000 IU/month of vitamin D3 for 12 months, with a significant reduction in the concentrations of glycated hemoglobin, fasting glucose, and two-hour postprandial glucose. Conclusion: there is insufficient scientific evidence to confirm the beneficial effects of vitamin D supplementation on glycemic control markers in pre-diabetic individuals.
关键词：Vitamina D;Prediabetes;Glucosa en ayunas;Insulina;Hemoglobina A glicada
其他关键词：Vitamin D;Pre-diabetes;Fasting glucose;Insulin;Glycated hemoglobin A